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However, this does not explain the fact that, in the ER, the ratio of reduced to oxidized glutathione ([GSH]:[GSSG]) is optimal for disulphide-bond formation (Lyles & Gilbert, 1991)

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Piperine-based triazoles 14 and 15 as selective cyclooxygenases-2 (COX-2)/tumor necrosis factor-alpha (TNF-) inhibitors With the rise of molecular hybridization as a promising approach in disease therapy, a new series of ursodeoxycholic acid-cinnamic acid hybrids was developed and synthesized